Premera Blue Cross of Washington prior authorization, page 3

CPT code lookup

Each row is one code from the public prior authorization list. The description is the procedure or service name on that source row. This is not a coverage decision.

Prior authorization codes

Prior authorization codes
CodeDescriptionSource
0232UCSTB (cystatin B) (eg, progressive myoclonic epilepsy type 1A, Unverricht- Lundborg disease), full gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) expansions, mobile element insertions, and variants in non-uniquely mappable regionsClinical Review by Code List PBCWA, Pg 48 Original policy
0233UFXN (frataxin) (eg, Friedreich ataxia), gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) expansions, mobile element insertions, and variants in non-uniquely mappable regions These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 48 Original policy
0234UMECP2 (methyl CpG binding protein 2) (eg, Rett syndrome), full gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, mobile element insertions, and variants in non-uniquely mappable regionsClinical Review by Code List PBCWA, Pg 49 Original policy
0235UPTEN (phosphatase and tensin homolog) (eg, Cowden syndrome, PTEN hamartoma tumor syndrome), full gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, mobile element insertions, and variants in non-uniquely mappable regionsClinical Review by Code List PBCWA, Pg 49 Original policy
0236USMN1 (survival of motor neuron 1, telomeric) and SMN2 (survival of motor neuron 2, centromeric) (eg, spinal muscular atrophy) full gene analysis, including small sequence changes in exonic and intronic regions, duplications and deletions, and mobile element insertions These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 49 Original policy
0237UCardiac ion channelopathies (eg, Brugada syndrome, long QT syndrome, short QT syndrome, catecholaminergic polymorphic ventricular tachycardia), genomic sequence analysis panel including ANK2, CASQ2, CAV3, KCNE1, KCNE2, KCNH2, KCNJ2, KCNQ1, RYR2, and SCN5A, including small sequence changes in exonic and intronic regions, deletions, duplications, mobile element insertions, and variants in non-uniquely mappable regionsClinical Review by Code List PBCWA, Pg 50 Original policy
0238TTransluminal peripheral atherectomy, open or percutaneous, including radiological supervision and interpretation; iliac artery, each vesselClinical Review by Code List PBCWA, Pg 50 Original policy
0238UOncology (Lynch syndrome), genomic DNA sequence analysis of MLH1, MSH2, MSH6, PMS2, and EPCAM, including small sequence changes in exonic and intronic regions, deletions, duplications, mobile element insertions, and variants in non- uniquely mappable regions These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 50 Original policy
0239UTargeted genomic sequence analysis panel, solid organ neoplasm, cell-free DNA, analysis of 311 or more genes, interrogation for sequence variants, including substitutions, insertions, deletions, select rearrangements, and copy number variationsClinical Review by Code List PBCWA, Pg 51 Original policy
0242UTargeted genomic seq analysis panel, solid organ neoplasm, cell-free circulating DNA analysis of 55-74 genes, inerrogation for seq variants, gene copy number amplificationsClinical Review by Code List PBCWA, Pg 51 Original policy
0244UOncology DNA, comprehensive genomic profiling, 257 genes, interrogation for single- nucleotide variants, insertions/deletions, copy number alterations, gene rearrangementsClinical Review by Code List PBCWA, Pg 52 Original policy
0245UOncology (thyroid) mutation analysis of 10 genes & 37 rna fusions & expression of 4 mrna markers using next-generation sequencing, fine needle aspirate, report incl associatedClinical Review by Code List PBCWA, Pg 52 Original policy
0250UOncology (solid organ neoplasm), targeted genomic sequence DNA analysis of 505 genes, interrogation for somatic alterations (SNVs [single nucleotide variant], small insertions and deletions, one amplification, and four translocations), microsatellite instability and tumor-mutation burdenClinical Review by Code List PBCWA, Pg 53 Original policy
0252UFetal aneuploidy short tandem-repeat comparative analysis, fetal DNA from products of conception, reported as normal (euploidy), monosomy, trisomy, or partial deletion/duplications, mosaicism, and segmental aneuploidyClinical Review by Code List PBCWA, Pg 53 Original policy
0253UReproductive medicine (endometrial receptivity analysis), RNA gene expression profile, 238 genes by next-generation sequencing, endometrial tissue, predictive algorithm reported as endometrial window of implantation (eg, pre-receptive, receptive, post-receptive) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 53 Original policy
0254UReproductive medicine (preimplantation genetic assessment), analysis of 24 chromosomes using embryonic DNA genomic sequence analysis for aneuploidy, and a mitochondrial DNA score in euploid embryos, results reported as normal (euploidy), monosomy, trisomy, or partial deletion/duplications, mosaicism, and segmental aneuploidy, per embryo testedClinical Review by Code List PBCWA, Pg 54 Original policy
0258UAutoimmune (psoriasis), mRNA, next- generation sequencing, gene expression profiling of 50-100 genes, skin-surface collection using adhesive patch, algorithm reported as likelihood of response to psoriasis biologicsClinical Review by Code List PBCWA, Pg 54 Original policy
0260URare diseases (constitutional/heritable disorders), identification of copy number variations, inversions, insertions, translocations, and other structural variants by optical genome mappingClinical Review by Code List PBCWA, Pg 54 Original policy
0262UOncology (solid tumor), gene expression profiling by real-time RT-PCR of 7 gene pathways (ER, AR, PI3K, MAPK, HH, TGFB, Notch), formalin-fixed paraffin- embedded (FFPE), algorithm reported as gene pathway activity score These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 54 Original policy
0264URare diseases (constitutional/heritable disorders), identification of copy number variations, inversions, insertions, translocations, and other structural variants by optical genome mappingClinical Review by Code List PBCWA, Pg 55 Original policy
0265URare constitutional and other heritable disorders, whole genome and mitochondrial DNA sequence analysis, blood, frozen and formalin-fixed paraffin-embedded (FFPE) tissue, saliva, buccal swabs or cell lines, identification of single nucleotide and copy number variants These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 55 Original policy
0266UUnexplained constitutional or other heritable disorders or syndromes, tissue- specific gene expression by whole- transcriptome and next-generation sequencing, blood, formalin-fixed paraffin- embedded (FFPE) tissue or fresh frozen tissue, reported as presence or absence of splicing or expression changesClinical Review by Code List PBCWA, Pg 56 Original policy
0267URare constitutional and other heritable disorders, identification of copy number variations, inversions, insertions, translocations, and other structural variants by optical genome mapping and whole genome sequencingClinical Review by Code List PBCWA, Pg 56 Original policy
0268UHematology (atypical hemolytic uremic syndrome [aHUS]), genomic sequence analysis of 15 genes, blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 56 Original policy
0269UHematology (autosomal dominant congenital thrombocytopenia), genomic sequence analysis of 22 genes, blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 56 Original policy
0270UHematology (congenital coagulation disorders), genomic sequence analysis of 20 genes, blood, buccal swab, or amniotic fluid These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 56 Original policy
0271UHematology (congenital neutropenia), genomic sequence analysis of 24 genes, blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 57 Original policy
0272UHematology (genetic bleeding disorders), genomic sequence analysis of 60 genes and duplication/deletion of plau, blood, buccal swab, or amniotic fluid, comprehensiveClinical Review by Code List PBCWA, Pg 57 Original policy
0273UHematology (genetic hyperfibrinolysis, delayed bleeding), genomic sequence analysis of 8 genes (F13A1, F13B, FGA, FGB, FGG, SERPINA1, SERPINE1, SERPINF2, PLAU), blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 57 Original policy
0274UHematology (genetic platelet disorders), genomic sequence analysis of 62 genes and duplication/deletion of plau, blood, buccal swab, or amniotic fluid These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 57 Original policy
0276UHematology (inherited thrombocytopenia), genomic sequence analysis of 42 genes, blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 58 Original policy
0277UHematology (genetic platelet function disorder), genomic sequence analysis of 40 genes and duplication/deletion of plau, blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 58 Original policy
0278UHematology (genetic thrombosis), genomic sequence analysis of 14 genes, blood, buccal swab, or amniotic fluidClinical Review by Code List PBCWA, Pg 58 Original policy
0285UOncology, disease progression and response monitoring to radiation, chemotherapy, or other systematic cancer treatments, cell-free DNA, quantitative branched chain DNA amplification, plasma reported in as NG/ML a radiation toxicity score These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 58 Original policy
0286UCEP72 (centrosomal protein, 72-KDa), NUDT15 (nudix hydrolase 15) and TPMT (thiopurine S-methyltransferase) (eg, drug metabolism) gene analysis, common variantsClinical Review by Code List PBCWA, Pg 59 Original policy
0287UOncology (thyroid), DNA and mRNA, next- generation sequencing analysis of 112 genes, fine needle aspirate or formalin- fixed paraffin-embedded (FFPE) tissue, algorithmic prediction of cancer recurrence, reported as a categorical risk result (low, intermediate, high)Clinical Review by Code List PBCWA, Pg 59 Original policy
0288UOncology (lung), mRNA, quantitative PCR analysis of 11 genes (BAG1, BRCA1, CDC6, CDK2AP1, ERBB3, FUT3, IL11, LCK, RND3, SH3BGR, WNT3A) and 3 reference genes (ESD, TBP, YAP1), formalin-fixed paraffin-embedded (FFPE) tumor tissue, algorithmic interpretation reported as a recurrence risk scoreClinical Review by Code List PBCWA, Pg 59 Original policy
0289UNeurology (Alzheimer disease), mRNA, gene expression profiling by RNA sequencing of 24 genes, whole blood, algorithm reported as predictive risk score These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 59 Original policy
0290UPain management, mRNA, gene expression profiling by RNA sequencing of 36 genes, whole blood, algorithm reported as predictive risk scoreClinical Review by Code List PBCWA, Pg 60 Original policy
0291UPsychiatry (mood disorders), mRNA, gene expression profiling by RNA sequencing of 144 genes, whole blood, algorithm reported as predictive risk scoreClinical Review by Code List PBCWA, Pg 60 Original policy
0292UPsychiatry (stress disorders), mRNA, gene expression profiling by RNA sequencing of 72 genes, whole blood, algorithm reported as predictive risk scoreClinical Review by Code List PBCWA, Pg 60 Original policy
0293UPsychiatry (suicidal ideation), mRNA, gene expression profiling by RNA sequencing of 54 genes, whole blood, algorithm reported as predictive risk scoreClinical Review by Code List PBCWA, Pg 60 Original policy
0294ULongevity and mortality risk, mRNA, gene expression profiling by RNA sequencing of 18 genes, whole blood, algorithm reported as predictive risk score These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 60 Original policy
0296UOncology (oral and/or oropharyngeal cancer), gene expression profiling by RNA sequencing of at least 20 molecular features (eg, human and/or microbial mRNA), saliva, algorithm reported as positive or negative for signature associated with malignancyClinical Review by Code List PBCWA, Pg 61 Original policy
0297UOncology (pan tumor), whole genome sequencing of paired malignant and normal DNA specimens, fresh or formalin-fixed paraffin-embedded (FFPE) tissue, blood or bone marrow, comparative sequence analyses and variant identification These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 61 Original policy
0298UOncology (pan tumor), whole transcriptome sequencing of paired malignant and normal RNA specimens, fresh or formalin-fixed paraffin-embedded (FFPE) tissue, blood or bone marrow, comparative sequence analyses and expression level and chimeric transcript identificationClinical Review by Code List PBCWA, Pg 62 Original policy
0299UOncology (pan tumor), whole genome optical genome mapping of paired malignant and normal DNA specimens, fresh frozen tissue, blood, or bone marrow, comparative structural variant identificationClinical Review by Code List PBCWA, Pg 62 Original policy
0300UOncology (pan tumor), whole genome sequencing and optical genome mapping of paired malignant and normal DNA specimens, fresh tissue, blood, or bone marrow, comparative sequence analyses and variant identification These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 62 Original policy
0306UOncology (minimal residual disease [MRD]), next-generation targeted sequencing analysis, cell-free DNA, initial (baseline) assessment to determine a patient specific panel for future comparisons to evaluate for MRDClinical Review by Code List PBCWA, Pg 63 Original policy
0307UOncology (minimal residual disease [MRD]), next-generation targeted sequencing analysis of a patient-specific panel, cell-free DNA, subsequent assessment with comparison to previously analyzed patient specimens to evaluate for MRDClinical Review by Code List PBCWA, Pg 63 Original policy

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