Premera Blue Cross of Washington prior authorization, page 2

CPT code lookup

Each row is one code from the public prior authorization list. The description is the procedure or service name on that source row. This is not a coverage decision.

Prior authorization codes

Prior authorization codes
CodeDescriptionSource
0103UHereditary ovarian cancer (eg, hereditary ovarian cancer, hereditary endometrial cancer); genomic sequence analysis panel utilizing a combination of ngs, sanger, mlpa and array cgh, with mrna analytics to resolve variants of unknown significance when indicated [24 genes (sequencing and deletion/duplication); epcam (deletion/duplication only)Clinical Review by Code List PBCWA, Pg 28 Original policy
0111UOncology (colon cancer), targeted KRAS (codons 12, 13, and 61) and NRAS (codons 12, 13, and 61) gene analysis utilizing formalin-fixed paraffin-embedded tissueClinical Review by Code List PBCWA, Pg 28 Original policy
0113UOncology (prostate), measurement of PCA3 and TMPRSS2-ERG in urine and PSA in serum following prostatic massage, by RNA amplification and fluorescence- based detection, algorithm reported as risk scoreClinical Review by Code List PBCWA, Pg 29 Original policy
0114UGastroenterology (Barrett's esophagus), VIM and CCNA1 methylation analysis, esophageal cells, algorithm reported as likelihood for Barrett's esophagusClinical Review by Code List PBCWA, Pg 29 Original policy
0118UTransplantation medicine, quantification of donor-derived cell-free DNA using whole genome next-generation sequencing, plasma, reported as percentage of donor- derived cell-free DNA in the total cell-free DNA These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 29 Original policy
0120UOncology (B-cell lymphoma classification), mRNA, gene expression profiling by fluorescent probe hybridization of 58 genes (45 content and 13 housekeeping genes), formalin-fixed paraffin-embedded tissue, algorithm reported as likelihood for primary mediastinal B-cell lymphoma (PMBCL) and diffuse large B-cell lymphoma (DLBCL) with cell of origin subtyping in the latterClinical Review by Code List PBCWA, Pg 30 Original policy
0129UHereditary breast cancer-related disorders (eg, hereditary breast cancer, hereditary ovarian cancer, hereditary endometrial cancer), genomic sequence analysis and deletion/duplication analysis panel (ATM, BRCA1, BRCA2, CDH1, CHEK2, PALB2, PTEN, and TP53)Clinical Review by Code List PBCWA, Pg 30 Original policy
0130UHereditary colon cancer disorders (eg, Lynch syndrome, PTEN hamartoma syndrome, Cowden syndrome, familial adenomatosis polyposis), targeted mRNA sequence analysis panel (APC, CDH1, CHEK2, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, and TP53) (List separately in addition to code for primary procedure) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 30 Original policy
0133UHereditary prostate cancer-related disorders, targeted mRNA sequence analysis panel (11 genes) (List separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 31 Original policy
0134UHereditary pan cancer (eg, hereditary breast and ovarian cancer, hereditary endometrial cancer, hereditary colorectal cancer), targeted mRNA sequence analysis panel (18 genes) (List separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 31 Original policy
0136UATM (ataxia telangiectasia mutated) (eg, ataxia telangiectasia) mRNA sequence analysis (List separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 31 Original policy
0137UPALB2 (partner and localizer of BRCA2) (eg, breast and pancreatic cancer) mRNA sequence analysis (List separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 31 Original policy
0138UBRCA1 (BRCA1, DNA repair associated), BRCA2 (BRCA2, DNA repair associated) (eg, hereditary breast and ovarian cancer) mRNA sequence analysis (List separately in addition to code for primary procedure) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 31 Original policy
0153UOncology (breast), MRNA, gene expression profiling by next-generation sequencing of 101 genes, utilizing formalin-fixed paraffin- embedded tissue, algorithm reported as a triple negative breast cancer clinical subtype(s) with information on immune cell involvementClinical Review by Code List PBCWA, Pg 32 Original policy
0154UOncology (urothelial cancer) RNA, analysis by real-time rt-pcr of the FGFR3 (fibroblast growth factor receptor 3) gene analysis (IE, P.R248C [C.742C>T], P.S249C [C.746C>G], P.G370C [C.1108G>T], P.Y373C [C.1118A>G], FGFR3-TACC3V1, AND FGFR3-TACC3V3) utilizing formalin- fixed paraffin-embedded (FFPE) urothelial cancer tumor tissue, reported as FGFR gene alteration statusClinical Review by Code List PBCWA, Pg 32 Original policy
0155UOncology (breast cancer) DNA, PIK3CA (PHOSPHATIDYLINOSITOL- 4,5BISPHOSPHATE 3-KINASE, catalytic SUBUNIT ALPHA) gene analysis (IE, P.C420R, P.E542K, P.E545A, P.E545D [G.1635G>T ONLY], P.E545G, P.E545K, P.Q546E, P.Q546R, P.H1047L, P.H1047R, P.H1047Y) utilizing formalin-fixed paraffin- embedded (FFPE) breast tumor tissue, reported as PIK3CA gene mutation status These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 32 Original policy
0156UCopy number (EG, intellectual disability, dysmorphology), sequence analysisClinical Review by Code List PBCWA, Pg 33 Original policy
0157UAPC (APC regulator of WNT signaling pathway) (EG, familial adenomatosis polyposis [FAP]) MRNA sequence analysis (list separately in addition to code for primary procedureClinical Review by Code List PBCWA, Pg 33 Original policy
0158UMLH1 (MUTL HOMOLOG 1) (EG, hereditary non-polyposis colorectal cancer, lynch syndrome) mrna sequence analysis (list separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 33 Original policy
0159UMSH2 (MUTS HOMOLOG 2) (EG, hereditary colon cancer, lynch syndrome) MRNA sequence analysis (list separately in addition to code for primary procedure) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 33 Original policy
0160UMSH6 (MUTS HOMOLOG 6) (EG, hereditary colon cancer, lynch syndrome) MRNA sequence analysis (list separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 34 Original policy
0161UPMS2 (PMS1 HOMOLOG 2, mismatch repair system component) (eg, hereditary nonpolyposis colorectal cancer, lynch syndrome) MRNA sequence analysis (list separately in addition to code for primary procedure)Clinical Review by Code List PBCWA, Pg 34 Original policy
0162UHereditary colon cancer (lynch syndrome), targeted MRNA sequence analysis panel (MLH1, MSH2, MSH6, PMS2) (list separately in addition to code for primary procedure) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 34 Original policy
0164TRemoval of total disc arthroplasty, anterior approach, lumbar, each additional interspace (List separately in addition to code for primary procedureClinical Review by Code List PBCWA, Pg 35 Original policy
0165TRevision of total disc arthroplasty (artificial disc),, anterior approach, lumbar, each additional interspaceClinical Review by Code List PBCWA, Pg 35 Original policy
0169UNUDT15 (nudix hydrolase 15) and TPMT (thiopurine S-methyltransferase) (eg, drug metabolism) gene analysis, common variantsClinical Review by Code List PBCWA, Pg 35 Original policy
0170UNeurology (autism spectrum disorder [ASD]), RNA, next-generation sequencing, saliva, algorithmic analysis, and results reported as predictive probability of ASD diagnosis These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 35 Original policy
0171UTargeted genomic sequence analysis panel, acute myeloid leukemia, myelodysplastic syndrome, and myeloproliferative neoplasms, DNA analysis, 23 genes, interrogation for sequence variants, rearrangements and minimal residual disease, reported as presence/absenceClinical Review by Code List PBCWA, Pg 36 Original policy
0172UOncology (solid tumor as indicated by the label), somatic mutation analysis of BRCA1 (BRCA1, DNA repair associated), BRCA2 (BRCA2, DNA repair associated) and analysis of homologous recombination deficiency pathways, DNA, formalin-fixed paraffin-embedded tissue, algorithm quantifying tumor genomic instability scoreClinical Review by Code List PBCWA, Pg 36 Original policy
0173UPsychiatry (ie, depression, anxiety), genomic analysis panel, includes variant analysis of 14 genesClinical Review by Code List PBCWA, Pg 36 Original policy
0175UPsychiatry (eg, depression, anxiety), genomic analysis panel, variant analysis of 15 genesClinical Review by Code List PBCWA, Pg 37 Original policy
0177UOncology (breast cancer), DNA, PIK3CA (phosphatidylinositol-4,5-bisphosphate 3- kinase catalytic subunit alpha) gene analysis of 11 gene variants utilizing plasma, reported as PIK3CA gene mutation statusClinical Review by Code List PBCWA, Pg 37 Original policy
0179UOncology (non-small cell lung cancer), cell- free DNA, targeted sequence analysis of 23 genes (single nucleotide variations, insertions and deletions, fusions without prior knowledge of partner/breakpoint, copy number variations), with report of significant mutation(s) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 37 Original policy
0200TPercutaneous sacral augmentation (sacroplasty), unilateral injection(s), including the use of a balloon or mechanical device, when used, 1 or more needlesClinical Review by Code List PBCWA, Pg 41 Original policy
0201TPercutaneous sacral augmentation (sacroplasty), bilateral injections, including the use of a balloon or mechanical device, when used, 2 or more needlesClinical Review by Code List PBCWA, Pg 41 Original policy
0203UAutoimmune (inflammatory bowel disease), mRNA, gene expression profiling by quantitative RT-PCR, 17 genes (15 target and 2 reference genes), whole blood, reported as a continuous risk score and classification of inflammatory bowel disease aggressiveness These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 41 Original policy
0205UOphthalmology (age-related macular degeneration), analysis of 3 gene variants (2 CFH gene, 1 ARMS2 gene), using PCR and MALDI-TOF, buccal swab, reported as positive or negative for neovascular age- related macular-degeneration risk associated with zinc supplementsClinical Review by Code List PBCWA, Pg 42 Original policy
0209UCytogenomic constitutional (genome-wide) analysis, interrogation of genomic regions for copy number, structural changes and areas of homozygosity for chromosomal abnormalitiesClinical Review by Code List PBCWA, Pg 42 Original policy
0211UOncology (pan-tumor), DNA and RNA by next-generation sequencing, utilizing formalin-fixed paraffin-embedded tissue, interpretative report for single nucleotide variants, copy number alterations, tumor mutational burden, and microsatellite instability, with therapy associationClinical Review by Code List PBCWA, Pg 43 Original policy
0212UOncology (pan-tumor), DNA and RNA by next-generation sequencing, utilizing formalin-fixed paraffin-embedded tissue, interpretative report for single nucleotide variants, copy number alterations, tumor mutational burden, and microsatellite instability, with therapy associationClinical Review by Code List PBCWA, Pg 43 Original policy
0213URare diseases (constitutional/heritable disorders), whole genome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non- uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, each comparator genome (eg, parent, sibling) These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 43 Original policy
0214URare diseases (constitutional/heritable disorders), whole exome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, probandClinical Review by Code List PBCWA, Pg 44 Original policy
0215URare diseases (constitutional/heritable disorders), whole exome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, each comparator exome (eg, parent, sibling)Clinical Review by Code List PBCWA, Pg 44 Original policy
0216UNeurology (inherited ataxias), genomic DNA sequence analysis of 12 common genes including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non- uniquely mappable regions, blood or saliva, identification and categorization of genetic variants These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 44 Original policy
0217UNeurology (inherited ataxias), genomic DNA sequence analysis of 51 genes including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non- uniquely mappable regions, blood or saliva, identification and categorization of genetic variantsClinical Review by Code List PBCWA, Pg 45 Original policy
0218UNeurology (muscular dystrophy), DMD gene sequence analysis, including small sequence changes, deletions, duplications, and variants in non-uniquely mappable regions, blood or saliva, identification and characterization of genetic variantsClinical Review by Code List PBCWA, Pg 45 Original policy
0228UOncology (prostate), multianalyte molecular profile by photometric detection of macromolecules adsorbed on nanosponge array slides with machine learning, utilizing first morning voided urine, algorithm reported as likelihood of prostate cancerClinical Review by Code List PBCWA, Pg 47 Original policy
0229UBCAT1 (Branched chain amino acid transaminase 1) or IKZF1 (IKAROS family zinc finger 1) (eg, colorectal cancer) promoter methylation analysisClinical Review by Code List PBCWA, Pg 47 Original policy
0230UAR (androgen receptor) (eg, spinal and bulbar muscular atrophy, Kennedy disease, X chromosome inactivation), full sequence analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) expansions, mobile element insertions, and variants in non-uniquely mappable regions These criteria do not imply or guarantee approval.Clinical Review by Code List PBCWA, Pg 47 Original policy
0231UCACNA1A (calcium voltage-gated channel subunit alpha 1A) (eg, spinocerebellar ataxia), full gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) gene expansions, mobile element insertions, and variants in non-uniquely mappable regionsClinical Review by Code List PBCWA, Pg 48 Original policy

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