Substrate AI

Put your revenue cycle on autopilot with AI

AI agents autonomously work claims from status to payment, continuously executing with precision and speed faster than any manual process

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3,800+

Payers covered via EDI, portals, and APIs

87%

Reduction in manual collections work

$250K

Claims auto-resolved without human touch

AI agents for every step in
your revenue cycle

From the moment a claim is submitted to final payment, Substrate's agents work autonomously to maximize recovery and minimize manual work.

ST*277*0001~ BHT*0085*08~ NM1*PR*2*BCBS~ STC*F0:1~ REF*1K*284719~ AMT*YU*1663~

Enhanced

{ "claimId": "284719-1", "status": "Finalized", "statusCode": "F4", "reasonCode": "X277", "reason": "Requested info not received", "billedAmt": 1663.00, "paidAmt": 0.00, "patResp": 0.00, "deniedAmt": 1663.00, "payer": "BCBSIL" }

AI Enhanced Claims Status

The only solution that combines EDI 276/277, clearinghouse data, browser automation, and direct APIs into a single unified response

Analyzing denial reason...

Retrieving records from EHR...

Verifying patient data...

Building appeal package...

Filing appeal to payer...

Checking claim status...

Autonomous Appeals & Denials

Our AI Agent detects claims needing medical records, validates against payer policies, retrieves documentation and then autonomously writes & submits appeals

Intelligent Payment & Exception Posting

Automatically posts payments and reconciles exceptions with intelligent matching. Handles partial payments, adjustments, and COB while flagging only true exceptions.

No outstanding claims

EOB verified

$23.06 offset applied

Reviewing...

Smart Patient Credit Refunds

Validates credit balances, checks for offsetting claims, and processes refunds within your limits. Tracks state compliance and maintains full audit trails autonomously.

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From setup to self-driving in days not months

Here's how it works

Step 1

Connect your systems

Integrate with your PM, EHR, and clearinghouse. No migration required. Most practices are live within 48 hours.

Step 2

Agents start learning

Our agents analyze your claims, map payer patterns, and build specific strategies. Every success gets securely stored.

Step 3

Autonomous resolution

Claims are monitored, researched, and resolved 24/7. Success rates compound over time as learned strategies accumulate.

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Enterprise-grade AI that actually works and gets smarter at scale

Full Audit Trail

Complete visibility into every agent action with screenshots and video recordings. Know exactly what happened, when, and why.

Human-in-the-Loop

When our agent is uncertain, it escalates to your team for verification. These cases get logged and learned from, so they rarely happen twice.

Predictive Insights

Track payer trends, denial patterns, and agent performance across your entire revenue cycle. Surface the signals that matter across your entire AR.

Intelligence behind every agent. The models and data that power every decision.

Policy Agent models payer policies and validates your medical records against specific coverage criteria.

Validates documentation before submission

Confirms medical necessity

Compares against payer-specific rules

Generates appeals that reference criteria

AI Document Review classifies and extracts data from any medical document automatically.

Faster and more accurate than humans

Identifies & categorizes documents

Extracts billing details & auth windows

Validates patient & claim data

Eligibility Agent verifies patient eligibility for claim routing, COB, and eligibility-based denials.

Catch issues before they become denials

Verifies coverage prior to submission

Fills COB gaps automatically

Routes claims based on verified eligibility

Need tailored automation?

Our AI engineers embed with your team to build & automate pipelines

Contact Sales →

Security first, from the ground-up

End-to-end encryption protects sensitive data in transit and at rest, ensuring complete confidentiality.

Zero-trust architecture verifies every request, reducing attack surfaces and preventing unauthorized access.

Regular security audits and compliance checks keep our infrastructure resilient against evolving threats.

Granular access controls allow precise permission management, securing data at every level of the system.

Trust & Security →

HIPAA

SOC2

Ready to automate?