Blue Cross Blue Shield Oklahoma prior authorization, page 16

CPT code lookup

Each row is one code from the public prior authorization list. The description is the procedure or service name on that source row. This is not a coverage decision.

Prior authorization codes

Prior authorization codes
CodeDescriptionSource
0299UOncology (Pan Tumor) Whole Genome Optical Genome Mapping Of Paired Malignant And Normal Dna Specimens Fresh Frozen Tissue Blood Or Bone Marrow Comparative Structural Variant Identification2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 125 Original policy
0300UOncology (Pan Tumor) Whole Genome Sequencing And Optical Genome Mapping Of Paired Malignant And Normal Dna Specimens Fresh Tissue Blood Or Bone Marrow Comparative Sequence Analyses And Variant Identification2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 126 Original policy
0306UOncology (Minimal Residual Disease [Mrd]) Next-Generation Targeted Sequencing Analysis Cell-Free Dna Initial (Baseline) Assessment To Determine A Patient Specific Panel For Future Comparisons To Evaluate For Mrd2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 126 Original policy
0307UOncology (Minimal Residual Disease [Mrd]) Next-Generation Targeted Sequencing Analysis Of A Patient- Specific Panel Cell-Free Dna Subsequent Assessment With Comparison To Previously Analyzed Patient Specimens To Evaluate For Mrd2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 126 Original policy
0313UOncology (Pancreas) Dna And Mrna Next-Generation Sequencing Analysis Of 74 Genes And Analysis Of Cea (Ceacam5) Gene Expression Pancreatic Cyst Fluid Algorithm Reported As A Categorical Result (Ie Negative Low Probability Of Neoplasia Or Positive High Probability Of Neoplasia)2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 126 Original policy
0314UOncology (Cutaneous Melanoma) Mrna Gene Expression Profiling By Rt-Pcr Of 35 Genes (32 Content And 3 Housekeeping) Utilizing Formalin- Fixed Paraffin-Embedded (Ffpe) Tissue Algorithm Reported As A Categorical Result (Ie Benign Intermediate Malignant)2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 127 Original policy
0315UOncology (Cutaneous Squamous Cell Carcinoma) Mrna Gene Expression Profiling By Rt-Pcr Of 40 Genes (34 Content And 6 Housekeeping) Utilizing Formalin- Fixed Paraffin-Embedded (Ffpe) Tissue Algorithm Reported As A Categorical Risk Result (Ie Class 1 Class 2A Class 2B)2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 127 Original policy
0317UOncology (Lung Cancer) Four-Probe Fish (3Q29 3P22.1 10Q22.3 10Cen) Assay Whole Blood Predictive Algorithmgenerated Evaluation Reported As Decreased Or Increased Risk For Lung Cancer2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 127 Original policy
0318UPediatrics (Congenital Epigenetic Disorders) Whole Genome Methylation Analysis By Microarray For 50 Or More Genes Blood2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 127 Original policy
0319UNephrology (Renal Transplant) Rna Expression By Select Transcriptome Sequencing Using Pretransplant Peripheral Blood Algorithm Reported As A Risk Score For Early Acute Rejection2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 127 Original policy
0320UNephrology (Renal Transplant) Rna Expression By Select Transcriptome Sequencing Using Posttransplant Peripheral Blood Algorithm Reported As A Risk Score For Acute Cellular Rejection2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 128 Original policy
0326UTargeted Genomic Sequence Analysis Panel Solid Organ Neoplasm Cell-Free Circulating Dna Analysis Of 83 Or More Genes Interrogation For Sequence Variants Gene Copy Number Amplifications Gene Rearrangements Microsatellite Instability And Tumor Mutational Burden2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 128 Original policy
0327UFetal Aneuploidy (Trisomy 13 18 And 21) Dna Sequence Analysis Of Selected Regions Using Maternal Plasma Algorithm Reported As A Risk Score For Each Trisomy Includes Sex Reporting If Performed2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 128 Original policy
0329UOncology (Neoplasia) Exome And Transcriptome Sequence Analysis For Sequence Variants Gene Copy Number Amplifications And Deletions Gene Rearrangements Microsatellite Instability And Tumor Mutational Burden Utilizing Dna And Rna From Tumor With Dna From Normal Blood Or Saliva For Subtraction Report Of Clinically Significant Mutation(S) With Therapy Associations2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 128 Original policy
0331UOncology (Hematolymphoid Neoplasia) Optical Genome Mapping For Copy Number Alterations And Gene Rearrangements Utilizing Dna From Blood Or Bone Marrow Report Of Clinically Significant Alternations2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 129 Original policy
0332UOncology (Pan-Tumor) Genetic Profiling Of 8 Dna-Regulatory (Epigenetic) Markers By Quantitative Polymerase Chain Reaction (Qpcr) Whole Blood Reported As A High Or Low Probability Of Responding To Immune Checkpoint-Inhibitor Therapy2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 129 Original policy
0333UOncology (Liver) Surveillance For Hepatocellular Carcinoma (Hcc) In Highrisk Patients Analysis Of Methylation Patterns On Circulating Cell-Free Dna (Cfdna) Plus Measurement Of Serum Of Afp/Afp- L3 And Oncoprotein Des- Gammacarboxy-Prothrombin (Dcp) Algorithm Reported As Normal Or Abnormal Result2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 129 Original policy
0334UOncology (Solid Organ) Targeted Genomic Sequence Analysis Formalin-Fixed Paraffinembedded (Ffpe) Tumor Tissue Dna Analysis 84 Or More Genes Interrogation For Sequence Variants Gene Copy Number Amplifications Gene Rearrangements Microsatellite Instability And Tumor Mutational Burden2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 129 Original policy
0335URare Diseases (Constitutional/Heritable Disorders) Whole Genome Sequence Analysis Including Small Sequence Changes Copy Number Variants Deletions Duplications Mobile Element Insertions Uniparental Disomy (Upd) Inversions Aneuploidy Mitochondrial Genome Sequence Analysis With Heteroplasmy And Large Deletions Short Tandem Repeat (Str) Gene Expansions Fetal Sample Identification And Categorization Of Genetic Variants2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 130 Original policy
0336URare Diseases (Constitutional/Heritable Disorders) Whole Genome Sequence Analysis Including Small Sequence Changes Copy Number Variants Deletions Duplications Mobile Element Insertions Uniparental Disomy (Upd) Inversions Aneuploidy Mitochondrial Genome Sequence Analysis With Heteroplasmy And Large Deletions Short Tandem Repeat (Str) Gene Expansions Blood Or Saliva Identification And Categorization Of Genetic Variants Each Comparator Genome (Eg Parent)2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 130 Original policy
0339UOncology (Prostate) Mrna Expression Profiling Of Hoxc6 And Dlx1 Reverse Transcription Polymerase Chain Reaction (Rt-Pcr) First-Void Urine Following Digital Rectal Examination Algorithm Reported As Probability Of High- Grade Cancer2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 130 Original policy
0340UOncology (Pan-Cancer) Analysis Of Minimal Residual Disease (Mrd) From Plasma With Assays Personalized To Each Patient Based On Prior Next-Generation Sequencing Of The Patient’S Tumor And Germline Dna Reported As Absence Or Presence Of Mrd With Disease-Burden Correlation If Appropriate2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 131 Original policy
0341UFetal Aneuploidy Dna Sequencing Comparative Analysis Fetal Dna From Products Of Conception Reported As Normal (Euploidy) Monosomy Trisomy Or Partial Deletion/Duplication Mosaicism And Segmental Aneuploid2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 131 Original policy
0343UOncology (Prostate) Exosome- Based Analysis Of 442 Small Noncoding Rnas (Sncrnas) By Quantitative Reverse Transcription Polymerase Chain Reaction (Rt- Qpcr) Urine Reported As Molecular Evidence Of No- Low- Intermediate- Or High-Risk Of Prostate Cancer2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 131 Original policy
0345UPsychiatry (Eg Depression Anxiety Attention Deficit Hyperactivity Disorder [Adhd]) Genomic Analysis Panel Variant Analysis Of 15 Genes Including Deletion/Duplication Analysis Of Cyp2D62026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 131 Original policy
0347UDrug Metabolism Or Processing (Multiple Conditions) Whole Blood Or Buccal Specimen Dna Analysis 16 Gene Report With Variant Analysis And Reported Phenotypes2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 131 Original policy
0348UDrug Metabolism Or Processing (Multiple Conditions) Whole Blood Or Buccal Specimen Dna Analysis 25 Gene Report With Variant Analysis And Reported Phenotypes2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 132 Original policy
0349UDrug Metabolism Or Processing (Multiple Conditions) Whole Blood Or Buccal Specimen Dna Analysis 27 Gene Report With Variant Analysis Including Reported Phenotypes And Impacted Gene- Drug Interactions2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 132 Original policy
0350UDrug Metabolism Or Processing (Multiple Conditions) Whole Blood Or Buccal Specimen Dna Analysis 27 Gene Report With Variant Analysis And Reported Phenotypes2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 132 Original policy
0355UApol1 (Apolipoprotein L1) (Eg Chronic Kidney Disease) Risk Variants (G1 G2)2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 132 Original policy
0356UOncology (Oropharyngeal Or Anal) Evaluation Of 17 Dna Biomarkers Using Droplet Digital Pcr (Ddpcr) Cell-Free Dna Algorithm Reported As A Prognostic Risk Score For Cancer Recurrence2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 132 Original policy
0362UOncology (Papillary Thyroid Cancer) Gene-Expression Profiling Via Targeted Hybrid Capture- Enrichment Rna Sequencing Of 82 Content Genes And 10 Housekeeping Genes Fine Needle Aspirate Or Formalin-Fixed Paraffinembedded (Ffpe) Tissue Algorithm Reported As One Of Three Molecular Subtypes2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 132 Original policy
0363UOncology (Urothelial) Mrna Gene- Expression Profiling By Real-Time Quantitative Pcr Of 5 Genes (Mdk Hoxa13 Cdc2 [Cdk1] Igfbp5 And Cxcr2) Utilizing Urine Algorithm Incorporates Age Sex Smoking History And Macrohematuria Frequency Reported As A Risk Score For Having Urothelial Carcinoma2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 133 Original policy
0364UOncology (Hematolymphoid Neoplasm) Genomic Sequence Analysis Using Multiplex (Pcr) And Next-Generation Sequencing With Algorithm Quantification Of Dominant Clonal Sequence(S) Reported As Presence Or Absence Of Minimal Residual Disease (Mrd) With Quantitation Of Disease Burden When Appropriate2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 133 Original policy
0368UOncology (Colorectal Cancer) Evaluation For Mutations Of Apc Braf Ctnnb1 Kras Nras Pik3Ca Smad4 And Tp53 And Methylation Markers (Myo1G Kcnq5 C9Orf50 Fli1 Clip4 Znf132 And Twist1) Multiplex Quantitative Polymerase Chain Reaction (Qpcr) Circulating Cell-Free Dna (Cfdna) Plasma Report Of Risk Score For Advanced Adenoma Or Colorectal Cancer2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 133 Original policy
0378URfc1 (Replication Factor C Subunit 1) Repeat Expansion Variant Analysis By Traditional And Repeat- Primed Pcr Blood Saliva Or Buccal Swab2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 133 Original policy
0379UTargeted Genomic Sequence Analysis Panel Solid Organ Neoplasm Dna (523 Genes) And Rna (55 Genes) By Nextgeneration Sequencing Interrogation For Sequence Variants Gene Copy Number Amplifications Gene Rearrangements Microsatellite Instability And Tumor Mutational Burden2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 134 Original policy
0380UDrug Metabolism (Adverse Drug Reactions And Drug Response) Targeted Sequence Analysis 20 Gene Variants And Cyp2D6 Deletion Or Duplication Analysis With Reported Genotype And Phenotype2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 134 Original policy
0388UOncology (Non-Small Cell Lung Cancer) Next-Generation Sequencing With Identification Of Single Nucleotide Variants Copy Number Variants Insertions And Deletions And Structural Variants In 37 Cancer-Related Genes Plasma With Report For Alteration Detection2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 134 Original policy
0389UPediatric Febrile Illness (Kawasaki Disease [Kd]) Interferon Alphainducible Protein 27 (Ifi27) And Mast Cell-Expressed Membrane Protein 1 (Mcemp1) Rna Using Reverse Transcription Polymerase Chain Reaction (Rt-Qpcr) Blood Reported As A Risk Score For Kd2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 134 Original policy
0391UOncology (Solid Tumor) Dna And Rna By Next-Generation Sequencing Utilizing Formalin-Fixed Paraffin- Embedded (Ffpe) Tissue 437 Genes Interpretive Report For Single Nucleotide Variants Splicesite Variants Insertions/Deletions Copy Number Alterations Gene Fusions Tumor Mutational Burden And Microsatellite Instability With Algorithm Quantifying Immunotherapy Response Score2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 135 Original policy
0392UDrug Metabolism (Depression Anxiety Attention Deficit Hyperactivity Disorder [Adhd]) Gene- Drug Interactions Variant Analysis Of 16 Genes Including Deletion/Duplication Analysis Of Cyp2D6 Reported As Impact Of Gene-Drug Interaction For Each Drug2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 135 Original policy
0396UObstetrics (Pre-Implantation Genetic Testing) Evaluation Of 300000 Dna Single-Nucleotide Polymorphisms (Snps) By Microarray Embryonic Tissue Algorithm Reported As A Probability For Single-Gene Germline Conditions2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 135 Original policy
0400UObstetrics (Expanded Carrier Screening) 145 Genes By Nextgeneration Sequencing Fragment Analysis And Multiplex Ligationdependent Probe Amplification Dna Reported As Carrier Positive Or Negative2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 135 Original policy
0401UCardiology (Coronary Heart Disease [Cad]) 9 Genes (12 Variants) Targeted Variant Genotyping Blood Saliva Or Buccal Swab Algorithm Reported As A Genetic Risk Score For A Coronary Event2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 136 Original policy
0403UOnc Prst8 Mrna 18 Gen Dre Ur2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 136 Original policy
0405UOncology (Pancreatic) 59 Methylation Haplotype Block Markers Next-Generation Sequencing Plasma Reported As Cancer Signal Detected Or Not Detected2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 136 Original policy
0409UOnc Sld Tum Dna 80 & Rna 362026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 136 Original policy
0410UOncology (Pancreatic) Dna Whole Genome Sequencing With 5- Hydroxymethylcytosine Enrichment Whole Blood Or Plasma Algorithm Reported As Cancer Detected Or Not Detected2026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 136 Original policy
0411UPsychiatry (Eg Depression Anxiety Attention Deficit Hyperactivity Disorder [Adhd]) Genomic Analysis Panel Variant Analysis Of 15 Genes Including Deletion/Duplication Analysis Of Cyp2D62026 Commercial Outpatient Medical Surgical Fully Insured Prior Authorization Codes, Pg 136 Original policy

Sources

Disclaimer

The information provided on this page is for general informational purposes only and does not constitute billing, coding, or reimbursement advice. Nothing on this page should be relied upon as a substitute for clinician assessment, professional billing guidance, or as a definitive statement of any payor's billing requirements or policies.

Payor agreements, fee schedules, and billing policies vary and are subject to change. Before submitting any claims related to maternity care services, including claims affected by the 2027 CPT code revisions, please consult the applicable payor agreements, coverage policies, and billing guidelines to confirm current requirements for their specific payor contracts.

Substrate makes no representation or warranty regarding the accuracy, completeness, or timeliness of the payor-specific information presented here. Providers are solely responsible for ensuring that all claims are submitted in accordance with applicable payor requirements, and Substrate assumes no liability for claim denials, underpayments, or other adverse outcomes arising from reliance on this information.