Anthem Blue Cross Blue Shield of Georgia prior authorization, page 28

CPT code lookup

Each row is one code from the public prior authorization list. The description is the procedure or service name on that source row. This is not a coverage decision.

Prior authorization codes

Prior authorization codes
CodeDescriptionSource
0401UCardiology (coronary heart disease [CHD]), 9 genes (12 variants), targeted variant genotyping, blood, saliva, or buccal swab, algorithm reported as a genetic risk score for a coronary eventStandard Local Prior Authorization Code List, Pg 75 Original policy
0402TCollagen cross-linking of cornea, including removal of the corneal epithelium, when performed, and intraoperative pachymetry, when performedStandard Local Prior Authorization Code List, Pg 75 Original policy
0403UOncology (prostate), mRNA, gene expression profiling of 18 genes, first-catch post-digital rectal examination urine (or processed first-catch urine), algorithm reported as percentage of likelihood of detecting clinically significant prostate cancerStandard Local Prior Authorization Code List, Pg 75 Original policy
0405UOncology (pancreatic), 59 methylation haplotype block markers, next-generation sequencing, plasma, reported as cancer signal detected or not detectedStandard Local Prior Authorization Code List, Pg 75 Original policy
0409UOncology (solid tumor), DNA (80 genes) and RNA (36 genes), by next-generation sequencing from plasma, including single nucleotide variants, insertions/deletions, copy number alterations, microsatellite instability, and fusions, report showing identified mutations with clinical actionabilityStandard Local Prior Authorization Code List, Pg 75 Original policy
0410UOncology (pancreatic), DNA, whole genome sequencing with 5-hydroxymethylcytosine enrichment, whole blood or plasma, algorithm reported as cancer detected or not detectedStandard Local Prior Authorization Code List, Pg 75 Original policy
0411UPsychiatry (eg, depression, anxiety, attention deficit hyperactivity disorder [ADHD]), genomic analysis panel, variant analysis of 15 genes, including deletion/duplication analysis of CYP2D6Standard Local Prior Authorization Code List, Pg 75 Original policy
0413UOncology (hematolymphoid neoplasm), optical genome mapping for copy number alterations, aneuploidy, and balanced/complex structural rearrangements, DNA from blood or bone marrow, report of clinically significant alterationsStandard Local Prior Authorization Code List, Pg 75 Original policy
0414UOncology (lung), augmentative algorithmic analysis of digitized whole slide imaging for 8 genes (ALK, BRAF, EGFR, ERBB2, MET, NTRK1-3, RET, ROS1), and KRAS G12C and PD-L1, if performed, formalin-fixed paraffin-embedded (FFPE) tissue, reported as positive or negative for each biomarkerStandard Local Prior Authorization Code List, Pg 75 Original policy
0417URare diseases (constitutional/heritable disorders), whole mitochondrial genome sequence with heteroplasmy detection and deletion analysis, nuclear-encoded mitochondrial gene analysis of 335 nuclear genes, including sequence changes, deletions, insertions, and copy number variants analysis, blood or saliva, identification and categorization of mitochondrial disorder-associated genetic variantsStandard Local Prior Authorization Code List, Pg 75 Original policy
0419UNeuropsychiatry (eg, depression, anxiety), genomic sequence analysis panel, variant analysis of 13 genes, saliva or buccal swab, report of each gene phenotypeStandard Local Prior Authorization Code List, Pg 75 Original policy
0420UOncology (urothelial), mRNA expression profiling by real-time quantitative PCR of MDK, HOXA13, CDC2, IGFBP5, and CXCR2 in combination with droplet digital PCR (ddPCR) analysis of 6 single- nucleotide polymorphisms (SNPs) genes TERT and FGFR3, urine, algorithm reported as a risk score for urothelial carcinomaStandard Local Prior Authorization Code List, Pg 76 Original policy
0422UOncology (pan-solid tumor), analysis of DNA biomarker response to anti-cancer therapy using cell-free circulating DNA, biomarker comparison to a previous baseline pre-treatment cell-free circulating DNA analysis using next-generation sequencing, algorithm reported as a quantitative change from baseline, including specific alterations, if appropriateStandard Local Prior Authorization Code List, Pg 76 Original policy
0424UOncology (prostate), exosome-based analysis of 53 small noncoding RNAs (sncRNAs) by quantitative reverse transcription polymerase chain reaction (RT-qPCR), urine, reported as no molecular evidence, low-, moderate- or elevated-risk of prostate cancerStandard Local Prior Authorization Code List, Pg 76 Original policy
0425UGenome (eg, unexplained constitutional or heritable disorder or syndrome), rapid sequence analysis, each comparator genome (eg, parents, siblings)Standard Local Prior Authorization Code List, Pg 76 Original policy
0426UGenome (eg, unexplained constitutional or heritable disorder or syndrome), ultra-rapid sequence analysisStandard Local Prior Authorization Code List, Pg 76 Original policy
0433UOncology (prostate), 5 DNA regulatory markers by quantitative PCR, whole blood, algorithm, including prostate-specific antigen, reported as likelihood of cancerStandard Local Prior Authorization Code List, Pg 76 Original policy
0434UDrug metabolism (adverse drug reactions and drug response), genomic analysis panel, variant analysis of 25 genes with reported phenotypesStandard Local Prior Authorization Code List, Pg 76 Original policy
0437UPsychiatry (anxiety disorders), mRNA, gene expression profiling by RNA sequencing of 15 biomarkers, whole blood, algorithm reported as predictive risk scoreStandard Local Prior Authorization Code List, Pg 76 Original policy
0438UDrug metabolism (adverse drug reactions and drug response), buccal specimen, gene-drug interactions, variant analysis of 33 genes, including deletion/duplication analysis of CYP2D6, including reported phenotypes and impacted gene-drug interactionsStandard Local Prior Authorization Code List, Pg 76 Original policy
0439UCardiology (coronary heart disease [CHD]), DNA, analysis of 5 single-nucleotide polymorphisms (SNPs) (rs11716050 [LOC105376934], rs6560711 [WDR37], rs3735222 [SCIN/LOC10798676Standard Local Prior Authorization Code List, Pg 76 Original policy
0440UCardiology (coronary heart disease [CHD]), DNA, analysis of 10 single-nucleotide polymorphisms (SNPs) (rs710987 [LINC010019], rs1333048 [CDKN2B-AS1], rs12129789 [KCND3], rs942Standard Local Prior Authorization Code List, Pg 76 Original policy
0444UOncology (solid organ neoplasia), targeted genomic sequence analysis panel of 361 genes, interrogation for gene fusions, translocations, or other rearrangements, using DNA froStandard Local Prior Authorization Code List, Pg 76 Original policy
0449UCarrier screening for severe inherited conditions (eg, cystic fibrosis, spinal muscular atrophy, beta hemoglobinopathies [including sickle cell disease], alpha thalassemia), rStandard Local Prior Authorization Code List, Pg 76 Original policy
0452UOncology (bladder), methylated PENK DNA detection by linear target enrichment-quantitative methylation-specific real-time PCR (LTE-qMSP), urine, reported as likelihood of bladStandard Local Prior Authorization Code List, Pg 76 Original policy
0453UOncology (colorectal cancer), cell-free DNA (cfDNA), methylation-based quantitative PCR assay (SEPTIN9, IKZF1, BCAT1, Septin9-2, VAV3, BCAN), plasma, reported as presence or aStandard Local Prior Authorization Code List, Pg 76 Original policy
0454URare diseases (constitutional/heritable disorders), identification of copy number variations, inversions, insertions, translocations, and other structural variants by opticalStandard Local Prior Authorization Code List, Pg 76 Original policy
0460UOncology, whole blood or buccal, DNA single- nucleotide polymorphism (SNP) genotyping by real- time PCR of 24 genes, with variant analysis and reported phenotypesStandard Local Prior Authorization Code List, Pg 76 Original policy
0461UOncology, pharmacogenomic analysis of single- nucleotide polymorphism (SNP) genotyping by real- time PCR of 24 genes, whole blood or buccal swab, with variant analysis, includinStandard Local Prior Authorization Code List, Pg 76 Original policy
0465UOncology (urothelial carcinoma), DNA, quantitative methylation-specific PCR of 2 genes (ONECUT2, VIM), algorithmic analysis reported as positive or negativeStandard Local Prior Authorization Code List, Pg 77 Original policy
0466UCardiology (coronary artery disease [CAD]), DNA, genome-wide association studies (564856 single- nucleotide polymorphisms [SNPs], targeted variant genotyping), patient lifestylStandard Local Prior Authorization Code List, Pg 77 Original policy
0467UOncology (bladder), DNA, next-generation sequencing (NGS) of 60 genes and whole genome aneuploidy, urine, algorithms reported as minimal residual disease (MRD) status positiveStandard Local Prior Authorization Code List, Pg 77 Original policy
0469URare diseases (constitutional/heritable disorders), whole genome sequence analysis for chromosomal abnormalities, copy number variants, duplications/deletions, inversions, unbStandard Local Prior Authorization Code List, Pg 77 Original policy
0471UOncology (colorectal cancer), qualitative real-time PCR of 35 variants of KRAS and NRAS genes (exons 2, 3, 4), formalin-fixed paraffin-embedded (FFPE), predictive, identificatStandard Local Prior Authorization Code List, Pg 77 Original policy
0473UOncology (solid tumor), next-generation sequencing (NGS) of DNA from formalin-fixed paraffin-embedded (FFPE) tissue with comparative sequence analysis from a matched normal spStandard Local Prior Authorization Code List, Pg 77 Original policy
0474UHereditary pan-cancer (eg, hereditary sarcomas, hereditary endocrine tumors, hereditary neuroendocrine tumors, hereditary cutaneous melanoma), genomic sequence analysis panelStandard Local Prior Authorization Code List, Pg 77 Original policy
0475UHereditary prostate cancer-related disorders, genomic sequence analysis panel using next- generation sequencing (NGS), Sanger sequencing, multiplex ligation-dependent probe ampStandard Local Prior Authorization Code List, Pg 77 Original policy
0476UDrug metabolism, psychiatry (eg, major depressive disorder, general anxiety disorder, attention deficit hyperactivity disorder [ADHD], schizophrenia), whole blood, buccal swabStandard Local Prior Authorization Code List, Pg 77 Original policy
0477UDrug metabolism, psychiatry (eg, major depressive disorder, general anxiety disorder, attention deficit hyperactivity disorder [ADHD], schizophrenia), whole blood, buccal swabStandard Local Prior Authorization Code List, Pg 77 Original policy
0478UOncology (non-small cell lung cancer), DNA and RNA, digital PCR analysis of 9 genes (EGFR, KRAS, BRAF, ALK, ROS1, RET, NTRK 1/2/3, ERBB2, and MET) in formalin-fixed paraffin-eStandard Local Prior Authorization Code List, Pg 77 Original policy
0485UOncology (solid tumor), cell-free DNA and RNA by next-generation sequencing, interpretative report for germline mutations, clonal hematopoiesis of indeterminate potential, andStandard Local Prior Authorization Code List, Pg 77 Original policy
0486UOncology (pan-solid tumor), next-generation sequencing analysis of tumor methylation markers present in cell-free circulating tumor DNA, algorithm reported as quantitative meaStandard Local Prior Authorization Code List, Pg 77 Original policy
0487UOncology (solid tumor), cell-free circulating DNA, targeted genomic sequence analysis panel of 84 genes, interrogation for sequence variants, aneuploidy-corrected gene copy nuStandard Local Prior Authorization Code List, Pg 77 Original policy
0488UObstetrics (fetal antigen noninvasive prenatal test), cell-free DNA sequence analysis for detection of fetal presence or absence of 1 or more of the Rh, C, c, D, E, Duffy (FyaStandard Local Prior Authorization Code List, Pg 77 Original policy
0489UObstetrics (single-gene noninvasive prenatal test), cell-free DNA sequence analysis of 1 or more targets (eg, CFTR, SMN1, HBB, HBA1, HBA2) to identify paternally inherited patStandard Local Prior Authorization Code List, Pg 77 Original policy
0493UTransplantation medicine, quantification of donor- derived cell-free DNA (cfDNA) using next- generation sequencing, plasma, reported as percentage of donor-derived cell-free DNAStandard Local Prior Authorization Code List, Pg 77 Original policy
0494URed blood cell antigen (fetal RhD gene analysis), next-generation sequencing of circulating cell-free DNA (cfDNA) of blood in pregnant individuals known to be RhD negative, reStandard Local Prior Authorization Code List, Pg 77 Original policy
0496UOncology (colorectal), cell-free DNA, 8 genes for mutations, 7 genes for methylation by real-time RT- PCR, and 4 proteins by enzyme-linked immunosorbent assay, blood, reportedStandard Local Prior Authorization Code List, Pg 77 Original policy
0497UOncology (prostate), mRNA gene-expression profiling by real-time RT-PCR of 6 genes (FOXM1, MCM3, MTUS1, TTC21B, ALAS1, and PPP2CA), utilizing formalin-fixed paraffin-embeddedStandard Local Prior Authorization Code List, Pg 77 Original policy
0498UOncology (colorectal), next-generation sequencing for mutation detection in 43 genes and methylation pattern in 45 genes, blood, and formalin-fixed paraffin-embedded (FFPE) tiStandard Local Prior Authorization Code List, Pg 78 Original policy

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