Anthem Blue Cross Blue Shield of California policy

California PPO Prior Authorization List

California PPO Prior Authorization List is a public Anthem Blue Cross Blue Shield of California policy. It lists 3,545 CPT or HCPCS codes, 2918 of them on the Anthem Blue Cross Blue Shield of California prior authorization list. Not a coverage decision; the payer's own document governs.

View the original policy (PDF) ↗

Check eligibility for free

No account required. Sign a BAA to see plan details, coordination of benefits and more

Payer
Anthem Blue Cross Blue Shield of California
Line of business
Commercial
States
CA
Source
www.anthem.com

Codes in this policy

The CPT and HCPCS codes the policy names. A policy can name a code it excludes. Prior authorization status is from the Anthem Blue Cross Blue Shield of California prior authorization list.

CodePrior authorizationDescription on the prior authorization listOther Anthem Blue Cross Blue Shield of California policies
00002Not listedPolicies naming 00002
00003Not listedPolicies naming 00003
00004Not listedPolicies naming 00004
00005Not listedPolicies naming 00005
00006Not listedPolicies naming 00006
00007Not listedPolicies naming 00007
00008Not listedPolicies naming 00008
00009Not listedPolicies naming 00009
00010Not listedPolicies naming 00010
00011Not listedPolicies naming 00011
00012Not listedPolicies naming 00012
00013Not listedPolicies naming 00013
00015Not listedPolicies naming 00015
00016Not listedPolicies naming 00016
00019Not listedPolicies naming 00019
0001UOn the listRed blood cell antigen typing, DNA, human erythrocyte antigen gene analysis of 35 antigens from 11 blood groups, utilizing whole blood, common RBC alleles reportedPolicies naming 0001U
00022Not listedPolicies naming 00022
00023Not listedPolicies naming 00023
00024Not listedPolicies naming 00024
00025Not listedPolicies naming 00025
00026Not listedPolicies naming 00026
00027Not listedPolicies naming 00027
00028Not listedPolicies naming 00028
00029Not listedPolicies naming 00029
0002MOn the listLiver disease, ten biochemical assays (ALT, A2- macroglobulin, apolipoprotein A-1, total bilirubin, GGT, haptoglobin, AST, glucose, total cholesterol and triglycerides) utilizing serum, prognostic algorithm reported as quantitative scores for fibrosis, steatosis and alcoholic steatohepatitis (ASH)Policies naming 0002M
00030Not listedPolicies naming 00030
00031Not listedPolicies naming 00031
00032Not listedPolicies naming 00032
00033Not listedPolicies naming 00033
00034Not listedPolicies naming 00034
00035Not listedPolicies naming 00035
00036Not listedPolicies naming 00036
00037Not listedPolicies naming 00037
00038Not listedPolicies naming 00038
00039Not listedPolicies naming 00039
0003MOn the listLiver disease, ten biochemical assays (ALT, A2- macroglobulin, apolipoprotein A-1, total bilirubin, GGT, haptoglobin, AST, glucose, total cholesterol and triglycerides) utilizing serum, prognostic algorithm reported as quantitative scores for fibrosis, steatosis and nonalcoholic steatohepatitis (NASH)Policies naming 0003M
00040Not listedPolicies naming 00040
00041Not listedPolicies naming 00041
00042Not listedPolicies naming 00042
00043Not listedPolicies naming 00043
00044Not listedPolicies naming 00044
00045Not listedPolicies naming 00045
00046Not listedPolicies naming 00046
00047Not listedPolicies naming 00047
00048Not listedPolicies naming 00048
00049Not listedPolicies naming 00049
00050Not listedPolicies naming 00050
00052Not listedPolicies naming 00052
00053Not listedPolicies naming 00053
00055Not listedPolicies naming 00055
00056Not listedPolicies naming 00056
00057Not listedPolicies naming 00057
00059Not listedPolicies naming 00059
0005UOn the listOncology (prostate) gene expression profile by real-time RT- PCR of 3 genes (ERG, PCA3, and SPDEF), urine, algorithm reported as risk scorePolicies naming 0005U
00061Not listedPolicies naming 00061
00062Not listedPolicies naming 00062
00063Not listedPolicies naming 00063
00064Not listedPolicies naming 00064
00065Not listedPolicies naming 00065
00067Not listedPolicies naming 00067
00068Not listedPolicies naming 00068
00069Not listedPolicies naming 00069
0006MOn the listOncology (hepatic), mRNA expression levels of 161 genes, utilizing fresh hepatocellular carcinoma tumor tissue, with alpha-fetoprotein level, algorithm reported as a risk classifier. Lab tests for alpha-fetoprotein and for mRNA gene expression profiling for 161 genes using fresh tumor tissue from hepatocellular carcinoma. The test also includes an algorithmic analysis using patient data and the lab test results to report a risk classification score.Policies naming 0006M
00071Not listedPolicies naming 00071
00072Not listedPolicies naming 00072
00073Not listedPolicies naming 00073
00075Not listedPolicies naming 00075
00076Not listedPolicies naming 00076
00077Not listedPolicies naming 00077
00079Not listedPolicies naming 00079
0007MOn the listOncology (gastrointestinal neuroendocrine tumors), real-time PCR expression analysis of 51 genes, utilizing whole peripheral blood, algorithm reported as a nomogram of tumor disease indexPolicies naming 0007M
00082Not listedPolicies naming 00082
00084Not listedPolicies naming 00084
00087Not listedPolicies naming 00087
00088Not listedPolicies naming 00088
00089Not listedPolicies naming 00089
00090Not listedPolicies naming 00090
00091Not listedPolicies naming 00091
00092Not listedPolicies naming 00092
00095Not listedPolicies naming 00095
00096Not listedPolicies naming 00096
00097Not listedPolicies naming 00097
00098Not listedPolicies naming 00098
00099Not listedPolicies naming 00099
00100Not listedPolicies naming 00100
00101Not listedPolicies naming 00101
00102Not listedPolicies naming 00102
00103Not listedPolicies naming 00103
00104Not listedPolicies naming 00104
00105Not listedPolicies naming 00105
00107Not listedPolicies naming 00107
00110Not listedPolicies naming 00110
00111Not listedPolicies naming 00111
00112Not listedPolicies naming 00112
00113Not listedPolicies naming 00113
00114Not listedPolicies naming 00114
00115Not listedPolicies naming 00115
00116Not listedPolicies naming 00116
00118Not listedPolicies naming 00118
0011MOn the listOncology, prostate cancer, mRNA expression assay of 12 genes (10 content and 2 housekeeping), RT-PCR test utilizing blood plasma and/or urine, algorithms to predict high-grade prostate cancer riskPolicies naming 0011M
00120Not listedPolicies naming 00120
00121Not listedPolicies naming 00121
00123Not listedPolicies naming 00123
00124Not listedPolicies naming 00124
00125Not listedPolicies naming 00125
00126Not listedPolicies naming 00126
00128Not listedPolicies naming 00128
00129Not listedPolicies naming 00129
0012MOn the listOncology (urothelial), mRNA, gene expression profiling by real-time quantitative PCR of five genes (MDK, HOXA13, CDC2 [CDK1], IGFBP5, and CXCR2), utilizing urine, algorithm reported as a risk score for having urothelial carcinomaPolicies naming 0012M
00130Not listedPolicies naming 00130
00131Not listedPolicies naming 00131
00132Not listedPolicies naming 00132
00133Not listedPolicies naming 00133
00134Not listedPolicies naming 00134
00135Not listedPolicies naming 00135
00137Not listedPolicies naming 00137
00138Not listedPolicies naming 00138
00139Not listedPolicies naming 00139
0013MOn the listOncology (urothelial), mRNA, gene expression profiling by real-time quantitative PCR of five genes (MDK, HOXA13, CDC2 [CDK1], IGFBP5, and CXCR2), utilizing urine, algorithm reported as a risk score for having recurrent urothelial carcinomaPolicies naming 0013M
00140Not listedPolicies naming 00140
00141Not listedPolicies naming 00141
00142Not listedPolicies naming 00142
00143Not listedPolicies naming 00143
00144Not listedPolicies naming 00144
00145Not listedPolicies naming 00145
00146Not listedPolicies naming 00146
00147Not listedPolicies naming 00147
00148Not listedPolicies naming 00148
00149Not listedPolicies naming 00149
00152Not listedPolicies naming 00152
00153Not listedPolicies naming 00153
00154Not listedPolicies naming 00154
00155Not listedPolicies naming 00155
00156Not listedPolicies naming 00156
00157Not listedPolicies naming 00157
00158Not listedPolicies naming 00158
00159Not listedPolicies naming 00159
00160Not listedPolicies naming 00160
00161Not listedPolicies naming 00161
00162Not listedPolicies naming 00162
0016MOn the listOncology (bladder), mRNA, microarray gene expression profiling of 209 genes, utilizing formalin-fixed paraffin- embedded tissue, algorithm reported as molecular subtype (luminal, luminal infiltrated, basal, basal claudin-low, neuroendocrine-like)Policies naming 0016M
0016UOn the listOncology (hematolymphoid neoplasia), RNA, BCR/ABL1 major and minor breakpoint fusion transcripts, quantitative PCR amplification, blood or bone marrow, report of fusion not detected or detected with quantitationPolicies naming 0016U
0017MOn the listOncology (diffuse large B-cell lymphoma [DLBCL]), mRNA, gene expression profiling by fluorescent probe hybridization of 20 genes, formalin-fixed paraffin-embedded tissue, algorithm reported as cell of originPolicies naming 0017M
0017UOn the listOncology (hematolymphoid neoplasia), JAK2 mutation, DNA, PCR amplification of exons 12-14 and sequence analysis, blood or bone marrow, report of JAK2 mutation not detected or detectedPolicies naming 0017U
0018MNot listedPolicies naming 0018M
0018UOn the listOncology (thyroid), microRNA profiling by RT-PCR of 10 microRNA sequences, utilizing fine needle aspirate, algorithm reported as a positive or negative result for moderate to high risk of malignancyPolicies naming 0018U
0019UOn the listOncology, RNA, gene expression by whole transcriptome sequencing, formalin-fixed paraffin embedded tissue or fresh frozen tissue, predictive algorithm reported as potential targets for therapeutic agentsPolicies naming 0019U
0022UOn the listTargeted genomic sequence analysis panel, non-small cell lung neoplasia, DNA and RNA analysis, 23 genes, interrogation for sequence variants and rearrangements, reported as presence or absence of variants and associated therapy(ies) to considerPolicies naming 0022U
0023UOn the listOncology (acute myelogenous leukemia), DNA, genotyping of internal tandem duplication, p.D835, p.I836, using mononuclear cells, reported as detection or non-detection of FLT3 mutation and indication for or against the use of midostaurinPolicies naming 0023U
0026UOn the listOncology (thyroid), DNA and mRNA of 112 genes, next- generation sequencing, fine needle aspirate of thyroid nodule, algorithmic analysis reported as a categorical result ("Positive, high probability of malignancy" or "Negative, low probability of malignancy)Policies naming 0026U
0027UOn the listJAK2 (Janus kinase 2) (e.g., myeloproliferative disorder) gene analysis, targeted sequence analysis exons 12-15Policies naming 0027U
0029UNot listedPolicies naming 0029U
0030UOn the listDrug metabolism (warfarin drug response), targeted sequence analysis (i.e., CYP2C9, CYP4F2, VKORC1, rs12777823)Policies naming 0030U
0031UNot listedPolicies naming 0031U
0032UOn the listCOMT (catechol-O-methyltransferase)(drug metabolism) gene analysis, c.472G>A (rs4680) variantPolicies naming 0032U
0033UNot listedPolicies naming 0033U
0034UOn the listTPMT (thiopurine S-methyltransferase), NUDT15 (nudix hydroxylase 15)(e.g., thiopurine metabolism), gene analysis, common variants (i.e., TPMT *2, *3A, *3B, *3C, *4, *5, *6, *8, *12; NUDT15 *3, *4, *5)Policies naming 0034U
0036UOn the listExome (i.e., somatic mutations), paired formalin-fixed paraffin- embedded tumor tissue and normal specimen, sequence analysesPolicies naming 0036U
0037UOn the listTargeted genomic sequence analysis, solid organ neoplasm, DNA analysis of 324 genes, interrogation for sequence variants, gene copy number amplifications, gene rearrangements, microsatellite instability and tumor mutational burdenPolicies naming 0037U
0040UOn the listBCR/ABL1 (t(9;22)) (e.g., chronic myelogenous leukemia) translocation analysis, major breakpoint, quantitativePolicies naming 0040U
0042TNot listedPolicies naming 0042T
0045UOn the listOncology (breast ductal carcinoma in situ), mRNA, gene expression profiling by realtime RT-PCR of 12 genes (7 content and 5 housekeeping), utilizing formalin-fixed paraffin- embedded tissue, algorithm reported as recurrence scorePolicies naming 0045U
0046UOn the listFLT3 (fms-related tyrosine kinase 3) (e.g., acute myeloid leukemia) internal tandem duplication (ITD) variants, quantitativePolicies naming 0046U
0047UOn the listOncology (prostate), mRNA, gene expression profiling by real- time RT-PCR of 17 genes (12 content and 5 housekeeping), utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a risk scorePolicies naming 0047U
0048UOn the listOncology (solid organ neoplasia), DNA, targeted sequencing of protein-coding exons of 468 cancer-associated genes, including interrogation for somatic mutations and microsatellite instability, matched with normal specimens, utilizing formalin-fixed paraffin-embedded tumor tissue, report of clinically significant mutation(s)Policies naming 0048U
0049UOn the listNPM1 (nucleophosmin) (e.g., acute myeloid leukemia) gene analysis, quantitativePolicies naming 0049U
0050UOn the listTargeted genomic sequence analysis panel, acute myelogenous leukemia, DNA analysis, 194 genes, interrogation for sequence variants, copy number variants or rearrangementsPolicies naming 0050U
0052UNot listedPolicies naming 0052U
00530Not listedPolicies naming 00530
0055UOn the listCardiology (heart transplant), cell-free DNA, PCR assay of 96 DNA target sequences (94 single nucleotide polymorphism targets and two control targets), plasmaPolicies naming 0055U
00580On the listAnesthesia for heart transplant or heart/lung transplantPolicies naming 00580
0062UNot listedPolicies naming 0062U
0069UOn the listOncology (colorectal), microRNA, RT-PCR expression profiling of miR-31-3p, formalin-fixed paraffin-embedded tissue, algorithm reported as an expression scorePolicies naming 0069U
0070UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, common and select rare variants (i.e., *2, *3, *4, *4N, *5, *6, *7, *8, *9, *10, *11, *12, *13, *14A, *14B, *15, *17, *29, *35, *36, *41, *57, *61, *63, *68, *83, *xN)Policies naming 0070U
0071TOn the listFocused ultrasound ablation of uterine leiomyomata, including MR guidance; total leiomyomata volume less than 200 cc of tissuePolicies naming 0071T
0071UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, full gene sequence (List separately in addition to code for primary procedure)Policies naming 0071U
0072TOn the listFocused ultrasound ablation of uterine leiomyomata, including MR guidance; total leiomyomata volume greater or equal to 200 cc of tissuePolicies naming 0072T
0072UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, targeted sequence analysis (i.e., CYP2D6-2D7 hybrid gene) (List separately in addition to code for primary procedure)Policies naming 0072U
00731On the listAnesthesia for upper gastrointestinal endoscopic procedures, endoscope introduced proximal to duodenum; not otherwise specifiedPolicies naming 00731
00732On the listAnesthesia for upper gastrointestinal endoscopic procedures; endoscopic retrograde cholangiopancreatography [ERCP]Policies naming 00732
0073UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, targeted sequence analysis (i.e., CYP2D7-2D6 hybrid gene) (List separately in addition to code for primary procedure)Policies naming 0073U
0074UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, targeted sequence analysis (i.e., non-duplicated gene when duplication/multiplication is trans) (List separately in addition to code for primary procedure)Policies naming 0074U
0075TNot listedPolicies naming 0075T
0075UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, targeted sequence analysis (i.e., 5’ gene duplication/multiplication) (List separately in addition to code for primary procedure)Policies naming 0075U
0076TNot listedPolicies naming 0076T
0076UOn the listCYP2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6) (e.g., drug metabolism) gene analysis, targeted sequence analysis (i.e., 3’ gene duplication/ multiplication) (List separately in addition to code for primary procedure)Policies naming 0076U
00796On the listAnesthesia for intraperitoneal procedures in upper abdomen including laparoscopy; liver transplant (recipient)Policies naming 00796
0079UOn the listComparative DNA analysis using multiple selected single- nucleotide polymorphisms (SNPs), urine and buccal DNA, for specimen identity verificationPolicies naming 0079U
0080UOn the listOncology (lung), mass spectrometric analysis of galectin-3- binding protein and scavenger receptor cysteine-rich type 1 protein M130, with five clinical risk factors (age, smoking status, nodule diameter, nodule-spiculation status and nodule location), utilizing plasma, algorithm reported as a categorical probability of malignancyPolicies naming 0080U
00811On the listAnesthesia for lower intestinal endoscopic procedures, endoscope introduced distal to duodenum; not otherwise specifiedPolicies naming 00811
00812On the listAnesthesia for upper gastrointestinal endoscopic procedures, endoscope introduced proximal to duodenum; not otherwise specified; screening colonoscopyPolicies naming 00812
00813On the listAnesthesia for combined upper and lower gastrointestinal endoscopic procedures, endoscope introduced both proximal to and distal to the duodenumPolicies naming 00813
0087UOn the listCardiology (heart transplant), mRNA gene expression profiling by microarray of 1283 genes, transplant biopsy tissue, allograft rejection and injury algorithm reported as a probability scorePolicies naming 0087U
0088UOn the listTransplantation medicine (kidney allograft rejection), microarray gene expression profiling of 1494 genes, utilizing transplant biopsy tissue, algorithm reported as a probability score for rejection.Policies naming 0088U
0089UOn the listOncology (melanoma), gene expression profiling by RTqPCR, PRAME and LINC00518, superficial collection using adhesive patch(es)Policies naming 0089U
0090UOn the listOncology (cutaneous melanoma), mRNA gene expression profiling by RT-PCR of 23 genes (14 content and 9 housekeeping), utilizing formalin-fixed paraffin-embedded (FFPE) tissue, algorithm reported as a categorical result (i.e., benign, intermediate, malignant)Policies naming 0090U
0091UNot listedPolicies naming 0091U
0092UNot listedPolicies naming 0092U
0094UOn the listGenome (e.g., unexplained constitutional or heritable disorder or syndrome), rapid sequence analysisPolicies naming 0094U
0095TOn the listRemoval of total disc arthroplasty (artificial disc), anterior approach, each additional interspace, cervical (List separately in addition to code for primary procedure)Policies naming 0095T
0098TOn the listRevision including replacement of total disc arthroplasty (artificial disc), anterior approach, each additional interspace, cervical (List separately in addition to code for primary procedure)Policies naming 0098T
0100TOn the listPlacement of a subconjunctival retinal prosthesis receiver and pulse generator, and implantation of intra-ocular retinal electrode array, with vitrectomyPolicies naming 0100T
0101TOn the listExtracorporeal shock wave involving musculoskeletal system, not otherwise specifiedPolicies naming 0101T
0101UOn the listHereditary colon cancer disorders (e.g., Lynch syndrome, PTEN hamartoma syndrome, Cowden syndrome, familial adenomatosis polyposis), genomic sequence analysis panel utilizing a combination of NGS, Sanger, MLPA, and array CGH, with MRNA analytics to resolve variants of unknown significance when indicated (15 genes [sequencing and deletion/duplication], EPCAM and GREM1 [deletion/duplication only])Policies naming 0101U
0102TOn the listExtracorporeal shock wave, performed by a physician, requiring anesthesia other than local, and involving the lateral humeral epicondylePolicies naming 0102T
0102UOn the listHereditary breast cancer-related disorders (e.g., hereditary breast cancer, hereditary ovarian cancer, hereditary endometrial cancer), genomic sequence analysis panel utilizing a combination of NGS, Sanger, MLPA, and array CGH, with MRNA analytics to resolve variants of unknown significance when indicated (17 genes [sequencing and deletion/duplication])Policies naming 0102U
0103UOn the listHereditary ovarian cancer (e.g., hereditary ovarian cancer, hereditary endometrial cancer), genomic sequence analysis panel utilizing a combination of NGS, Sanger, MLPA, and array CGH, with MRNA analytics to resolve variants of unknown significance when indicated (24 genes [sequencing and deletion/duplication], EPCAM [deletion/duplication only])Policies naming 0103U
0105UOn the listNephrology (chronic kidney disease), multiplex electrochemiluminescent immunoassay (ECLIA) of tumor necrosis factor receptor 1A, receptor superfamily 2 (TNFR1, TNFR2), and kidney injury molecule-1 (KIM-1) combined with longitudinal clinical data, including APOL1 genotype if available, and plasma (isolated fresh or frozen), algorithm reported as probability score for rapid kidney function decline (RKFD)Policies naming 0105U
0106TOn the listQuantitative sensory testing (QST), testing and interpretation per extremity; using touch pressure stimuli to assess large diameter sensationPolicies naming 0106T
0107TOn the listQuantitative sensory testing (QST), testing and interpretation per extremity; using vibration stimuli to assess large diameter fiber sensationPolicies naming 0107T
0108TOn the listQuantitative sensory testing (QST), testing and interpretation per extremity; using cooling stimuli to assess small nerve fiber sensation and hyperalgesiaPolicies naming 0108T
0109TOn the listQuantitative sensory testing (QST), testing and interpretation per extremity; using heat-pain stimuli to assess small nerve fiber sensation and hyperalgesiaPolicies naming 0109T
0110TOn the listQuantitative sensory testing (QST), testing and interpretation per extremity; using other stimuli to assess sensationPolicies naming 0110T
0111UOn the listOncology (colon cancer), targeted KRAS (codons 12, 13, and 61) and NRAS (codons 12, 13, and 61) gene analysis utilizing formalin-fixed paraffin-embedded tissuePolicies naming 0111U
0112UOn the listInfectious agent detection and identification, targeted sequence analysis (16S and 18S rRNA genes) with drug- resistance genePolicies naming 0112U
0113UOn the listOncology (prostate), measurement of PCA3 and TMPRSS2- ERG in urine and PSA in serum following prostatic massage, by RNA amplification and fluorescence-based detection, algorithm reported as risk scorePolicies naming 0113U
0117UOn the listPain management, analysis of 11 endogenous analytes (methylmalonic acid, xanthurenic acid, homocysteine, pyroglutamic acid, vanilmandelate, 5-hydroxyindoleacetic acid, hydroxymethylglutarate, ethylmalonate, 3-hydroxypropyl mercapturic acid (3-HPMA), quinolinic acid, kynurenic acid), LC-MS/MS, urine, algorithm reported as a pain-index score with likelihood of atypical biochemical function associated with painPolicies naming 0117U
0118UOn the listTransplantation medicine, quantification of donor-derived cell- free DNA using whole genome next-generation sequencing, plasma, reported as percentage of donor-derived cell-free DNA in the total cell-free DNA [when specified for heart transplant rejection]Policies naming 0118U
0120UOn the listOncology (B-cell lymphoma classification), mRNA, gene expression profiling by fluorescent probe hybridization of 58 genes (45 content and 13 housekeeping genes), formalin- fixed paraffin-embedded tissue, algorithm reported as likelihood for primary mediastinal B-cell lymphoma (PMBCL) and diffuse large B-cell lymphoma (DLBCL) with cell of origin subtyping in the latterPolicies naming 0120U
0130UOn the listHereditary colon cancer disorders (e.g., Lynch syndrome, PTEN hamartoma syndrome, Cowden syndrome, familial adenomatosis polyposis), targeted mRNA sequence analysis panel (APC, CDH1, CHEK2, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, and TP53)Policies naming 0130U
0131UNot listedPolicies naming 0131U
0132UNot listedPolicies naming 0132U
0133UOn the listHereditary prostate cancer-related disorders, targeted mRNA sequence analysis panel (11 genes)Policies naming 0133U
0134UOn the listHereditary pan cancer (e.g., hereditary breast and ovarian cancer, hereditary endometrial cancer, hereditary colorectal cancer), targeted mRNA sequence analysis panel (18 genes) (List separately in addition to code for primary procedure)Policies naming 0134U
0135UNot listedPolicies naming 0135U
0136UOn the listATM (ataxia telangiectasia mutated) (e.g., ataxia telangiectasia) mRNA sequence analysisPolicies naming 0136U
0137UOn the listPALB2 (partner and localizer of BRCA2) (e.g., breast and pancreatic cancer) mRNA sequence analysisPolicies naming 0137U
0138UOn the listBRCA1 (BRCA1, DNA repair associated), BRCA2 (BRCA2, DNA repair associated) (e.g., hereditary breast and ovarian cancer) mRNA sequence analysisPolicies naming 0138U
0141UNot listedPolicies naming 0141U
0142UNot listedPolicies naming 0142U
0152UOn the listInfectious disease (bacteria, fungi, parasites, and DNA viruses), DNA, plasma, untargeted next-generation sequencing, report for significant positive pathogensPolicies naming 0152U
0153UOn the listOncology (breast), mRNA, gene expression profiling by next- generation sequencing of 101 genes, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a triple negative breast cancer clinical subtype(s) with information on immune cell involvementPolicies naming 0153U
0154UOn the listOncology (urothelial cancer), RNA, analysis by real-time RT- PCR of the FGFR3 (fibroblast growth factor receptor 3) gene analysis (i.e., p.R248C [c.742C>T], p.S249C [c.746C>G], p.G370C [c.1108G>T], p.Y373C [c.1118A>G], FGFR3- TACC3v1, and FGFR3-TACC3 v3), utilizing formalin-fixed paraffin-embedded urothelial cancer tumor tissue, reported as FGFR gene alteration statusPolicies naming 0154U
0155UOn the listOncology (breast cancer), DNA, PIK3CA (phosphatidylinositol- 4,5- bisphosphate 3-kinase, catalytic subunit alpha) (e.g., breast cancer) gene analysis (i.e., p.C420R, p.E542K, p.E545A, p.E545D [g.1635G>T only], p.E545G, p.E545K, p.Q546E, p.Q546R, p.H1047L, p.H1047R, p.H1047Y), utilizing formalin-fixed paraffin-embedded breast tumor tissue, reported as PIK3CA gene mutation statusPolicies naming 0155U
0156UOn the listCopy number (e.g., intellectual disability, dysmorphology), sequence analysisPolicies naming 0156U
0157UOn the listAPC (APC regulator of WNT signaling pathway) (e.g., familial adenomatosis polyposis [FAP]) mRNA sequence analysisPolicies naming 0157U
0158UOn the listMLH1 (mutL homolog 1) (e.g., hereditary non-polyposis colorectal cancer, Lynch syndrome) mRNA sequence analysisPolicies naming 0158U
0159UOn the listMSH2 (mutS homolog 2) (e.g., hereditary colon cancer, Lynch syndrome) mRNA sequence analysisPolicies naming 0159U
0160UOn the listMSH6 (mutS homolog 6) (e.g., hereditary colon cancer, Lynch syndrome) mRNA sequence analysisPolicies naming 0160U
0161UOn the listPMS2 (PMS1 homolog 2, mismatch repair system component) (e.g., hereditary non-polyposis colorectal cancer, Lynch syndrome) mRNA sequence analysisPolicies naming 0161U
0162UOn the listHereditary colon cancer (Lynch syndrome), targeted mRNA sequence analysis panel (MLH1, MSH2, MSH6, PMS2)Policies naming 0162U
0164TNot listedPolicies naming 0164T
0164UOn the listGastroenterology (irritable bowel syndrome [IBS]), immunoassay for antiCdtB and anti-vinculin antibodies, utilizing plasma, algorithm for elevated or not elevated qualitative resultsPolicies naming 0164U
0165TNot listedPolicies naming 0165T
0166UOn the listLiver disease, 10 biochemical assays (α2-macroglobulin, haptoglobin, apolipoprotein A1, bilirubin, GGT, ALT, AST, triglycerides, cholesterol, fasting glucose) and biometric and demographic data, utilizing serum, algorithm reported as scores for fibrosis, necroinflammatory activity, and steatosis with a summary interpretationPolicies naming 0166U
0169UOn the listNUDT15 (nudix hydrolase 15) and TPMT (thiopurine S- methyltransferase) (e.g., drug metabolism) gene analysis, common variantsPolicies naming 0169U
0170UOn the listNeurology (autism spectrum disorder [ASD]), RNA, next- generation sequencing, saliva, algorithmic analysis, and results reported as predictive probability of ASD diagnosisPolicies naming 0170U
0171UOn the listTargeted genomic sequence analysis panel, acute myeloid leukemia, myelodysplastic syndrome, and myeloproliferative neoplasms, DNA analysis, 23 genes, interrogation for sequence variants, rearrangements and minimal residual disease, reported as presence/absencePolicies naming 0171U
0172UOn the listOncology (solid tumor as indicated by the label), somatic mutation analysis of BRCA1 (BRCA1, DNA repair associated), BRCA2 (BRCA2, DNA repair associated) and analysis of homologous recombination deficiency pathways, DNA, formalin-fixed paraffin-embedded tissue, algorithm quantifying tumor genomic instability scorePolicies naming 0172U
0173UOn the listPsychiatry (i.e., depression, anxiety), genomic analysis panel, includes variant analysis of 14 genesPolicies naming 0173U
0174UNot listedPolicies naming 0174U
0175UOn the listPsychiatry (e.g., depression, anxiety), genomic analysis panel, variant analysis of 15 genesPolicies naming 0175U
0176UNot listedPolicies naming 0176U
0177UOn the listOncology (breast cancer), DNA, PIK3CA (phosphatidylinositol- 4,5-bisphosphate 3-kinase catalytic subunit alpha) gene analysis of 11 gene variants utilizing plasma, reported as PIK3CA gene mutation statusPolicies naming 0177U
0179UOn the listOncology (non-small cell lung cancer), cell-free DNA, targeted sequence analysis of 23 genes (single nucleotide variations, insertions and deletions, fusions without prior knowledge of partner/breakpoint, copy number variations), with report of significant mutation(s)Policies naming 0179U
01937On the listAnesthesia for percutaneous image-guided injection, drainage or aspiration procedures on the spine or spinal cord; cervical or thoracicPolicies naming 01937
01938On the listAnesthesia for percutaneous image-guided injection, drainage or aspiration procedures on the spine or spinal cord; lumbar or sacralPolicies naming 01938
01939On the listAnesthesia for percutaneous image-guided destruction procedures by neurolytic agent on the spine or spinal cord; cervical or thoracicPolicies naming 01939
01940On the listAnesthesia for percutaneous image-guided destruction procedures by neurolytic agent on the spine or spinal cord; lumbar or sacralPolicies naming 01940
01941On the listAnesthesia for percutaneous image-guided neuromodulation or intravertebral procedures (e.g., kyphoplasty, vertebroplasty) on the spine or spinal cord; cervical or thoracicPolicies naming 01941
01942On the listAnesthesia for percutaneous image-guided neuromodulation or intravertebral procedures (e.g., kyphoplasty, vertebroplasty) on the spine or spinal cord; lumbar or sacralPolicies naming 01942
01991On the listAnesthesia for diagnostic or therapeutic nerve blocks and injections (when block or injection is performed by a different physician or other qualified health care professional); other than the prone positionPolicies naming 01991
01992On the listAnesthesia for diagnostic or therapeutic nerve blocks and injections (when block or injection is performed by a different physician or other qualified health care professional); prone positionPolicies naming 01992
0200TOn the listPercutaneous sacral augmentation (sacroplasty), unilateral injection(s), including the use of a balloon or mechanical device, when used, 1 or more needlesPolicies naming 0200T
0201TOn the listPercutaneous sacral augmentation (sacroplasty), bilateral injections, including the use of a balloon or mechanical device, when used, 2 or more needlesPolicies naming 0201T
0202TOn the listPosterior vertebral joint(s) arthroplasty (e.g., facet joint[s] replacement) including facetectomy, laminectomy, foraminotomy and vertebral column fixation, with or without injection of bone cement, including fluoroscopy, single level, lumbar spinePolicies naming 0202T
0203UOn the listAutoimmune (inflammatory bowel disease), mRNA, gene expression profiling by quantitative RT-PCR, 17 genes (15 target and 2 reference genes), whole blood, reported as a continuous risk score and classification of inflammatory bowel disease aggressivenessPolicies naming 0203U
0205UOn the listOphthalmology (age-related macular degeneration), analysis of 3 gene variants (2 CFH gene, 1 ARMS2 gene), using PCR and MALDI-TOF, buccal swab, reported as positive or negative for neovascular age-related macular-degeneration risk associated with zinc supplementsPolicies naming 0205U
0206UNot listedPolicies naming 0206U
0207TOn the listEvacuation of meibomian glands, automated, using heat and intermittent pressure, unilateralPolicies naming 0207T
0207UOn the listNeurology (Alzheimer disease); quantitative imaging of phosphorylated ERK1 and ERK2 in response to bradykinin treatment by in situ immunofluorescence, using cultured skin fibroblasts, reported as a probability index for Alzheimer diseasePolicies naming 0207U
0209UOn the listCytogenomic constitutional (genome-wide) analysis, interrogation of genomic regions for copy number, structural changes and areas of homozygosity for chromosomal abnormalitiesPolicies naming 0209U
0211UOn the listOncology (pan-tumor), DNA and RNA by next-generation sequencing, utilizing formalin-fixed paraffin-embedded tissue, interpretative report for single nucleotide variants, copy number alterations, tumor mutational burden, and microsatellite instability, with therapy associationPolicies naming 0211U
0212UOn the listRare diseases (constitutional/heritable disorders), whole genome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, probandPolicies naming 0212U
0213TOn the listInjection(s), diagnostic or therapeutic agent, paravertebral facet (zygapophyseal) joint (or nerves innervating that joint) with ultrasound guidance, cervical or thoracic; single levelPolicies naming 0213T
0213UOn the listRare diseases (constitutional/heritable disorders), whole genome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, each comparator genome (e.g., parent, sibling)Policies naming 0213U
0214TOn the listInjection(s), diagnostic or therapeutic agent, paravertebral facet (zygapophyseal) joint (or nerves innervating that joint) with ultrasound guidance, cervical or thoracic; second level (List separately in addition to code for primary procedure)Policies naming 0214T
0214UOn the listRare diseases (constitutional/heritable disorders), whole exome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, probandPolicies naming 0214U
0215TOn the listInjection(s), diagnostic or therapeutic agent, paravertebral facet (zygapophyseal) joint (or nerves innervating that joint) with ultrasound guidance, cervical or thoracic; third and any additional level(s) (List separately in addition to code for primary procedure)Policies naming 0215T
0215UOn the listRare diseases (constitutional/heritable disorders), whole exome and mitochondrial DNA sequence analysis, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variants, each comparator exome (e.g., parent, sibling)Policies naming 0215U
0216TOn the listInjection(s), diagnostic or therapeutic agent, paravertebral facet (zygapophyseal) joint (or nerves innervating that joint) with ultrasound guidance, lumbar or sacral; single levelPolicies naming 0216T
0216UOn the listNeurology (inherited ataxias), genomic DNA sequence analysis of 12 common genes including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variantsPolicies naming 0216U
0217TOn the listInjection(s), diagnostic or therapeutic agent, paravertebral facet (zygapophyseal) joint (or nerves innervating that joint) with ultrasound guidance, lumbar or sacral; second level (List separately in addition to code for primary procedure)Policies naming 0217T
0217UOn the listNeurology (inherited ataxias), genomic DNA sequence analysis of 51 genes including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions, blood or saliva, identification and categorization of genetic variantsPolicies naming 0217U
0218TNot listedPolicies naming 0218T
0218UOn the listNeurology (muscular dystrophy), DMD gene sequence analysis, including small sequence changes, deletions, duplications, and variants in non-uniquely mappable regions, blood or saliva, identification and characterization of genetic variantsPolicies naming 0218U
0219TNot listedPolicies naming 0219T
0220TNot listedPolicies naming 0220T
0221TNot listedPolicies naming 0221T
0222TNot listedPolicies naming 0222T
0228TOn the listInjection(s), anesthetic agent and/or steroid, transforaminal epidural, with ultrasound guidance, cervical or thoracic; single levelPolicies naming 0228T
0228UNot listedPolicies naming 0228U
0229TOn the listInjection(s), anesthetic agent and/or steroid, transforaminal epidural, with ultrasound guidance, cervical or thoracic; each additional level (List separately in addition to code for primary procedure)Policies naming 0229T
0229UOn the listBCAT1 (Branched chain amino acid transaminase 1) or IKZF1 (IKAROS family zinc finger 1) (e.g., colorectal cancer) promoter methylation analysisPolicies naming 0229U
0230TOn the listInjection(s), anesthetic agent and/or steroid, transforaminal epidural, with ultrasound guidance, lumbar or sacral; single levelPolicies naming 0230T
0230UOn the listAR (androgen receptor) (e.g., spinal and bulbar muscular atrophy, Kennedy disease, X chromosome inactivation), full sequence analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) expansions, mobile element insertions, and variants in non-uniquely mappable regionsPolicies naming 0230U
0231TOn the listInjection(s), anesthetic agent and/or steroid, transforaminal epidural, with ultrasound guidance, lumbar or sacral; each additional level (List separately in addition to code for primary procedure)Policies naming 0231T
0231UOn the listCACNA1A (calcium voltage-gated channel subunit alpha 1A) (e.g., spinocerebellar ataxia), full gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) gene expansions, mobile element insertions, and variants in non- uniquely mappable regionsPolicies naming 0231U
0232TOn the listInjection(s), platelet rich plasma, any tissue, including image guidance, harvesting and preparation when performedPolicies naming 0232T
0232UOn the listCSTB (cystatin B) (e.g., progressive myoclonic epilepsy type 1A, Unverricht-Lundborg disease), full gene analysis, including small sequence changes in exonic and intronic regions, deletions, duplications, short tandem repeat (STR) expansions, mobile element insertions, and variants in non- uniquely mappable regionsPolicies naming 0232U

And 3,245 more in the original policy.

All Anthem Blue Cross Blue Shield of California policies · Anthem Blue Cross Blue Shield of California prior authorization CPT list

Disclaimer

The information provided on this page is for general informational purposes only and does not constitute billing, coding, or reimbursement advice. Nothing on this page should be relied upon as a substitute for clinician assessment, professional billing guidance, or as a definitive statement of any payor's billing requirements or policies.

Payor agreements, fee schedules, and billing policies vary and are subject to change. Before submitting any claims related to maternity care services, including claims affected by the 2027 CPT code revisions, please consult the applicable payor agreements, coverage policies, and billing guidelines to confirm current requirements for their specific payor contracts.

Substrate makes no representation or warranty regarding the accuracy, completeness, or timeliness of the payor-specific information presented here. Providers are solely responsible for ensuring that all claims are submitted in accordance with applicable payor requirements, and Substrate assumes no liability for claim denials, underpayments, or other adverse outcomes arising from reliance on this information.